Trim26 (NM_001025599) Mouse Recombinant Protein
Product Specifications
Background
E3 ubiquitin-protein ligase which regulates the IFN-beta production and antiviral response downstream of various DNA-encoded pattern-recognition receptors (PRRs) . Promotes nuclear IRF3 ubiquitination and proteasomal degradation. Bridges together TBK1 and NEMO during the innate response to viral infection leading to the activation of TBK1.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse tripartite motif-containing 26 (Trim26), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
AI462198; Zfp173; Zfp1736
Gene ID
22670
UniProt
Q99PN3
Accession Number mRNA
NM_001025599
Chromosomal Location
17 19.16 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
62.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Trim26
Species
Mouse
Protein ID
NP_001020770
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/22670
Uniprot URL
https://www.uniprot.org/uniprot/Q99PN3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001025599
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001020770
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