Arx (NM_007492) Mouse Recombinant Protein
Product Specifications
Background
This gene encodes a transcription factor that plays an important role in the development of forebrain. Male mice lacking this gene have smaller brains, olfactory bulbs and testes, and die within half a day after birth. Mice lacking this gene specifically in ganglionic eminence-derived neurons, including cortical interneurons, develop seizures. Mutations in this gene have been demonstrated to cause mouse phenotypes resembling human X-linked lissencephaly and cognitive disability with epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Synonyms
Ar; Arx1
Gene ID
11878
UniProt
O35085
Accession Number mRNA
NM_007492
Chromosomal Location
X 41.05 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
58.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Arx
Species
Mouse
Protein ID
NP_031518
Overview
Purified recombinant protein of Mouse aristaless related homeobox (Arx), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/11878
Uniprot URL
https://www.uniprot.org/uniprot/O35085
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_007492
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_031518
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