Snx33 (NM_175483) Mouse Recombinant Protein
Product Specifications
Background
Plays a role in the reorganization of the cytoskeleton, endocytosis and cellular vesicle trafficking via its interactions with membranes, WASL, DNM1 and DNM2. Acts both during interphase and at the end of mitotic cell divisions. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Modulates endocytosis of cell-surface proteins, such as APP and PRNP; this then modulates the secretion of APP and PRNP peptides. Promotes membrane tubulation (in vitro) . May promote the formation of macropinosomes (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse sorting nexin 33 (Snx33), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
E130307J07Rik; Sh3px3
Gene ID
235406
UniProt
Q4VAA7
Accession Number mRNA
NM_175483
Chromosomal Location
9 B
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
65.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Snx33
Species
Mouse
Protein ID
NP_780692
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/235406
Uniprot URL
https://www.uniprot.org/uniprot/Q4VAA7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_175483
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_780692
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