Orc2 (NM_008765) Mouse Recombinant Protein
Product Specifications
Background
Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication (By similarity) . Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3. Stabilizes LRWD1, by protecting it from ubiquitin-mediated proteasomal degradation. Also stabilizes ORC3 (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
AU041563; Orc2l
Gene ID
18393
UniProt
Q60862, Q543F8
Accession Number mRNA
NM_008765
Chromosomal Location
1 C1.3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
65.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Orc2
Species
Mouse
Protein ID
NP_032791
Overview
Purified recombinant protein of Mouse origin recognition complex, subunit 2 (Orc2), transcript variant a, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/18393
Uniprot URL
https://www.uniprot.org/uniprot/Q60862
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_008765
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_032791
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
