Trafd1 (NM_172275) Mouse Recombinant Protein
Product Specifications
Background
Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse TRAF type zinc finger domain containing 1 (Trafd1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
1110008K06Rik; Fln29
Gene ID
231712
UniProt
Q3UDK1
Accession Number mRNA
NM_172275
Chromosomal Location
5 F
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
63.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Trafd1
Species
Mouse
Protein ID
NP_758479
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/231712
Uniprot URL
https://www.uniprot.org/uniprot/Q3UDK1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_172275
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_758479
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