Pomgnt2 (NM_153540) Mouse Recombinant Protein

Product Specifications

Background

O-linked mannose beta-1,4-N-acetylglucosaminyltransferase that transfers UDP-N-acetyl-D-glucosamine to the 4-position of the mannose to generate N-acetyl-D-glucosamine-beta-1,4-O-D-mannosylprotein (By similarity) . Involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4- (phosphate-6-) mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (PubMed:24256719) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse protein O-linked mannose beta 1, 4-N-acetylglucosaminyltransferase 2 (Pomgnt2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

Ago61; C85492; Gtdc2

Gene ID

215494

UniProt

Q8BW41

Accession Number mRNA

NM_153540

Chromosomal Location

9 F4

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

66.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.