Gckr (NM_144909) Mouse Recombinant Protein
Selected Variant
PM45594M5
Size: 20 µg
Product Specifications
Background
Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse glucokinase regulatory protein (Gckr), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
GKRP
Gene ID
231103
UniProt
Q91X44
Accession Number mRNA
NM_144909
Chromosomal Location
5 17.27 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
65.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Gckr
Species
Mouse
Protein ID
NP_659158
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/231103
Uniprot URL
https://www.uniprot.org/uniprot/Q91X44
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_144909
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_659158
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