C8b (NM_133882) Mouse Recombinant Protein
Product Specifications
Background
This gene encodes the beta subunit of complement component C8 that participates in the assembly of the complement membrane attack complex. The encoded preproprotein undergoes proteolytic processing to generate the beta subunit, which associates with the alpha and gamma subunits to form a trimeric complement component, C8. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. This gene is located adjacent to the gene encoding the alpha subunit. [provided by RefSeq, Oct 2015]
Synonyms
4930439B20Rik; AI595927
Gene ID
110382
UniProt
Q8BH35
Accession Number mRNA
NM_133882
Chromosomal Location
4 48.61 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
66.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
C8b
Species
Mouse
Protein ID
NP_598643
Overview
Purified recombinant protein of Mouse complement component 8, beta polypeptide (C8b), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/110382
Uniprot URL
https://www.uniprot.org/uniprot/Q8BH35
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_133882
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_598643
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