Rangap1 (NM_011241) Mouse Recombinant Protein

Product Specifications

Background

GTPase activator for RAN. Converts cytoplasmic GTP-bound RAN to GDP-bound RAN, which is essential for RAN-mediated nuclear import and export (PubMed:18305100) . Mediates dissociation of cargo from nuclear export complexes containing XPO1, RAN and RANBP2 after nuclear export (By similarity) . Required for postimplantation embryonic development (PubMed:8314081) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse RAN GTPase activating protein 1 (Rangap1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

C79654; Fug1; mKIAA1835

Gene ID

19387

UniProt

P46061

Accession Number mRNA

NM_011241

Chromosomal Location

15 38.21 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

63.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.