Rangap1 (NM_011241) Mouse Recombinant Protein
Product Specifications
Background
GTPase activator for RAN. Converts cytoplasmic GTP-bound RAN to GDP-bound RAN, which is essential for RAN-mediated nuclear import and export (PubMed:18305100) . Mediates dissociation of cargo from nuclear export complexes containing XPO1, RAN and RANBP2 after nuclear export (By similarity) . Required for postimplantation embryonic development (PubMed:8314081) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse RAN GTPase activating protein 1 (Rangap1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
C79654; Fug1; mKIAA1835
Gene ID
19387
UniProt
P46061
Accession Number mRNA
NM_011241
Chromosomal Location
15 38.21 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
63.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Rangap1
Species
Mouse
Protein ID
NP_035371
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/19387
Uniprot URL
https://www.uniprot.org/uniprot/P46061
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_011241
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_035371
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