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Nelfcd (NM_020580) Mouse Recombinant Protein

Product Specifications

Background

Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II (By similarity) . The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse negative elongation factor complex member C/D, Th1l (Nelfcd), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

2410003I03Rik; C77797; Th1; Th1l

Gene ID

57314

UniProt

Q922L6

Accession Number mRNA

NM_020580

Chromosomal Location

2 H4

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

66.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Nelfcd

Species

Mouse

Protein ID

NP_065605

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/57314

Uniprot URL

https://www.uniprot.org/uniprot/Q922L6

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_020580

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_065605

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