Setd3 (BC019973) Mouse Recombinant Protein

Product Specifications

Background

Protein-histidine N-methyltransferase that specifically mediates methylation of actin at 'His-73' (PubMed:30626964) . Histidine methylation of actin is required for smooth muscle contraction of the laboring uterus during delivery (PubMed:30626964) . Does not have protein-lysine N-methyltransferase activity and probably only catalyzes histidine methylation of actin (PubMed:30626964) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse SET domain containing 3 (cDNA clone MGC:28544 IMAGE:4195130), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

2610102I01Rik; 2610305M23Rik; 6030490B17Rik; D12Ertd771e

Gene ID

52690

UniProt

Q91WC0

Accession Number mRNA

BC019973

Chromosomal Location

12 59.23 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

90.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.