Setd3 (BC019973) Mouse Recombinant Protein
Product Specifications
Background
Protein-histidine N-methyltransferase that specifically mediates methylation of actin at 'His-73' (PubMed:30626964) . Histidine methylation of actin is required for smooth muscle contraction of the laboring uterus during delivery (PubMed:30626964) . Does not have protein-lysine N-methyltransferase activity and probably only catalyzes histidine methylation of actin (PubMed:30626964) .[UniProtKB/Swiss-Prot Function]
Synonyms
2610102I01Rik; 2610305M23Rik; 6030490B17Rik; D12Ertd771e
Gene ID
52690
UniProt
Q91WC0
Accession Number mRNA
BC019973
Chromosomal Location
12 59.23 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
90.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Setd3
Species
Mouse
Overview
Purified recombinant protein of Mouse SET domain containing 3 (cDNA clone MGC:28544 IMAGE:4195130), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/52690
Uniprot URL
https://www.uniprot.org/uniprot/Q91WC0
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/BC019973
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