4930432K21Rik (NM_029045) Mouse Recombinant Protein
Product Specifications
Background
Meiotic recombination factor component of recombination bridges involved in meiotic double-strand break repair (PubMed:32463460, PubMed:32460033) . Modulates the localization of recombinases DMC1:RAD51 to meiotic double-strand break (DSB) sites through the interaction with and stabilization of the BRCA2:HSF2BP complex during meiotic recombination (PubMed:32460033, PubMed:32463460) . Indispensable for the DSB repair, homologous synapsis, and crossover formation that are needed for progression past metaphase I, is essential for spermatogenesis and male fertility (PubMed:32463460, PubMed:32460033) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse RIKEN cDNA 4930432K21 gene (4930432K21Rik), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID
74666
UniProt
Q6DIA7, E9QNR8, A0A0R4J144
Accession Number mRNA
NM_029045
Chromosomal Location
8 C2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
64.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
4930432K21Rik
Species
Mouse
Protein ID
NP_083321
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/74666
Uniprot URL
https://www.uniprot.org/uniprot/Q6DIA7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_029045
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_083321
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