Lta4h (NM_008517) Mouse Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is an enzyme that contains both hydrolase and aminopeptidase activities. The hydrolase activity is used in the final step of the biosynthesis of leukotriene B4, a proinflammatory mediator. The aminopeptidase activity has been shown to degrade proline-glycine-proline (PGP), a neutrophil chemoattractant and biomarker for chronic obstructive pulmonary disease (COPD) . Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]

Overview

Purified recombinant protein of Mouse leukotriene A4 hydrolase (Lta4h), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Gene ID

16993

UniProt

P24527

Accession Number mRNA

NM_008517

Chromosomal Location

10 C2

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

69 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.