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F2 (NM_010168) Mouse Recombinant Protein

Product Specifications

Background

This gene encodes a vitamin K-dependent glycoprotein coagulation factor that plays an important role in the process of blood coagulation and hemostasis. The encoded protein is an inactive zymogen that undergoes enzymatic cleavage by the coagulation factor Xa to form an active serine protease that converts soluble fibrinogen to insoluble fibrin clot. Most of the mice lacking the encoded protein die at an embryonic stage due to defects in yolk sac vasculature, while the rare nenonates succumb to hemorrhage on the first postnatal day. [provided by RefSeq, Apr 2015]

Overview

Purified recombinant protein of Mouse coagulation factor II (F2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

Cf-2; Cf2; F; FII; prot; thro

Gene ID

14061

UniProt

P19221, Q3TJ94

Accession Number mRNA

NM_010168

Chromosomal Location

2 50.63 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

70.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

F2

Species

Mouse

Protein ID

NP_034298

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/14061

Uniprot URL

https://www.uniprot.org/uniprot/P19221

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_010168

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_034298

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