Dync1i1 (NM_010063) Mouse Recombinant Protein
Selected Variant
PM45439M5
Size: 20 µg
Product Specifications
Background
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse dynein cytoplasmic 1 intermediate chain 1 (Dync1i1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
DH IC-1; DHIC-1; DIC; Dncic1; IC74
Gene ID
13426
UniProt
O88485
Accession Number mRNA
NM_010063
Chromosomal Location
6 2.26 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
70.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Dync1i1
Species
Mouse
Protein ID
NP_034193
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/13426
Uniprot URL
https://www.uniprot.org/uniprot/O88485
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_010063
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_034193
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