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Ccdc93 (NM_001025156) Mouse Recombinant Protein

Product Specifications

Background

Component of the CCC complex, which is involved in the regulation of endosomal recycling of surface proteins, including integrins, signaling receptor and channels. The CCC complex associates with SNX17, retriever and WASH complexes to prevent lysosomal degradation and promote cell surface recycling of numerous cargos such as integrins ITGA5:ITGB1. Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery; the function is proposed to depend on its association within the CCC complex and cooperation with the WASH complex on early endosomes and is dependent on its interaction with WASHC2C.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse coiled-coil domain containing 93 (Ccdc93), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

4633402D15Rik; 9230102M16Rik

Gene ID

70829

UniProt

Q7TQK5

Accession Number mRNA

NM_001025156

Chromosomal Location

1 E2.3

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

72.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Ccdc93

Species

Mouse

Protein ID

NP_001020327

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/70829

Uniprot URL

https://www.uniprot.org/uniprot/Q7TQK5

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001025156

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001020327

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