Ubash3b (NM_176860) Mouse Recombinant Protein
Product Specifications
Background
Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface. Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70. Down-regulates proteins that are dually modified by both protein tyrosine phosphorylation and ubiquitination.[UniProtKB/Swiss-Prot Function]
Synonyms
2810457I06Rik; BB125008; p70; TULA-2
Gene ID
72828
UniProt
Q8BGG7
Accession Number mRNA
NM_176860
Chromosomal Location
9 A5.1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
71.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Ubash3b
Species
Mouse
Protein ID
NP_789830
Overview
Purified recombinant protein of Mouse ubiquitin associated and SH3 domain containing, B (Ubash3b), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/72828
Uniprot URL
https://www.uniprot.org/uniprot/Q8BGG7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_176860
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_789830
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
