Inpp5e (NM_033134) Mouse Recombinant Protein
Product Specifications
Background
Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns (3,4,5) P3), phosphatidylinositol 4,5-bisphosphate (PtdIns (4,5) P2) and phosphatidylinositol 3,5-bisphosphate (PtdIns (3,5) P2) . Specific for lipid substrates, inactive towards water soluble inositol phosphates. Specific for lipid substrates, inactive towards water soluble inositol phosphates (By similarity) (PubMed:10806194) . Plays an essential role in the primary cilium by controlling ciliary growth and phosphoinositide 3-kinase (PI3K) signaling and stability (PubMed:19668215) .[UniProtKB/Swiss-Prot Function]
Synonyms
72kDa; 1200002L24Rik; mKIAA0123
Gene ID
64436
UniProt
Q9JII1
Accession Number mRNA
NM_033134
Chromosomal Location
2 A3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
71.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Inpp5e
Species
Mouse
Protein ID
NP_149125
Overview
Purified recombinant protein of Mouse inositol polyphosphate-5-phosphatase E (Inpp5e), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/64436
Uniprot URL
https://www.uniprot.org/uniprot/Q9JII1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_033134
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_149125
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