Inpp5e (NM_033134) Mouse Recombinant Protein

Product Specifications

Background

Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns (3,4,5) P3), phosphatidylinositol 4,5-bisphosphate (PtdIns (4,5) P2) and phosphatidylinositol 3,5-bisphosphate (PtdIns (3,5) P2) . Specific for lipid substrates, inactive towards water soluble inositol phosphates. Specific for lipid substrates, inactive towards water soluble inositol phosphates (By similarity) (PubMed:10806194) . Plays an essential role in the primary cilium by controlling ciliary growth and phosphoinositide 3-kinase (PI3K) signaling and stability (PubMed:19668215) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse inositol polyphosphate-5-phosphatase E (Inpp5e), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

72kDa; 1200002L24Rik; mKIAA0123

Gene ID

64436

UniProt

Q9JII1

Accession Number mRNA

NM_033134

Chromosomal Location

2 A3

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

71.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.