Mcam (NM_023061) Mouse Recombinant Protein
Product Specifications
Background
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse melanoma cell adhesion molecule (Mcam), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
1-gicerin; AV025631; CD146; CD149; Muc18; s-endo; s-gicerin
Gene ID
84004
UniProt
Q8R2Y2
Accession Number mRNA
NM_023061
Chromosomal Location
9 A5.1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
71.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Mcam
Species
Mouse
Protein ID
NP_075548
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/84004
Uniprot URL
https://www.uniprot.org/uniprot/Q8R2Y2
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_023061
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_075548
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