Gpsm1 (BC071197) Mouse Recombinant Protein
Product Specifications
Background
Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G-protein signaling. Keeps G (i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse G-protein signalling modulator 1 (AGS3-like, C, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
1810037C22Rik; Ags3; AW107933
Gene ID
67839
UniProt
Q6IR34
Accession Number mRNA
BC071197
Chromosomal Location
2 A3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
73 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Gpsm1
Species
Mouse
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/67839
Uniprot URL
https://www.uniprot.org/uniprot/Q6IR34
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/BC071197
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