Wrnip1 (NM_030215) Mouse Recombinant Protein
Product Specifications
Background
Functions as a modulator of initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. In the presence of ATP, stimulation of DNA polymerase delta-mediated DNA synthesis is decreased. Plays also a role in the innate immune defense against viruses. Stabilizes the RIG-I/DDX58 dsRNA interaction and promotes RIG-I/DDX58 'Lys-63'-linked polyubiquitination. In turn, RIG-I/DDX58 transmits the signal through mitochondrial MAVS.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse Werner helicase interacting protein 1 (Wrnip1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
4833444L21Rik; WHIP; Wrnip
Gene ID
78903
UniProt
Q91XU0
Accession Number mRNA
NM_030215
Chromosomal Location
13 A3.2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
72.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Wrnip1
Species
Mouse
Protein ID
NP_084491
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/78903
Uniprot URL
https://www.uniprot.org/uniprot/Q91XU0
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_030215
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_084491
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