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Wdr48 (BC048155) Mouse Recombinant Protein

Product Specifications

Background

Regulator of deubiquitinating complexes. Acts as a strong activator of USP1 and USP46. Enhances the USP1-mediated deubiquitination of FANCD2; USP1 being almost inactive by itself. Also activates deubiquitinating activity of complexes containing USP12. Activates deubiquitination by increasing the catalytic turnover without increasing the affinity of deubiquitinating enzymes for the substrate.[UniProtKB/Swiss-Prot Function]

Synonyms

8430408H12Rik; mKIAA1449; Uaf1

Gene ID

67561

UniProt

Q8BH57

Accession Number mRNA

BC048155

Chromosomal Location

9 F4

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

74.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Wdr48

Species

Mouse

Overview

Purified recombinant protein of Mouse WD repeat domain 48 (cDNA clone MGC:61205 IMAGE:5698339), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/67561

Uniprot URL

https://www.uniprot.org/uniprot/Q8BH57

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/BC048155

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