Sema7a (NM_011352) Mouse Recombinant Protein
Product Specifications
Background
Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.[UniProtKB/Swiss-Prot Function]
Synonyms
2900057C09Rik; CDw108; H-Sema-L; M-Sema-L; Semal
Gene ID
20361
UniProt
Q9QUR8
Accession Number mRNA
NM_011352
Chromosomal Location
9 B
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
75.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Sema7a
Species
Mouse
Protein ID
NP_035482
Overview
Purified recombinant protein of Mouse sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A (Sema7a), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/20361
Uniprot URL
https://www.uniprot.org/uniprot/Q9QUR8
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_011352
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_035482
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