Hps4 (NM_138646) Mouse Recombinant Protein
Selected Variant
PM45318M5
Size: 20 µg
Product Specifications
Background
Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor (GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form. The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and promotes the membrane localization of RAB32 and RAB38.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse HPS4, biogenesis of lysosomal organelles complex 3 subunit 2 (Hps4), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
2010205O06Rik; AU040608; BLOC-3; C130020P05Rik; le; mKIAA1667
Gene ID
192232
UniProt
Q99KG7, Q541V2
Accession Number mRNA
NM_138646
Chromosomal Location
5 54.69 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
72.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Hps4
Species
Mouse
Protein ID
NP_619587
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/192232
Uniprot URL
https://www.uniprot.org/uniprot/Q99KG7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_138646
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_619587
Price
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