Gpsm2 (NM_029522) Mouse Recombinant Protein
Selected Variant
PM45317M5
Size: 20 µg
Product Specifications
Background
Plays an important role in mitotic spindle pole organization via its interaction with NUMA1 (PubMed:21816348) . Required for cortical dynein-dynactin complex recruitment during metaphase (By similarity) . Plays a role in metaphase spindle orientation (By similarity) . Plays an important role in asymmetric cell divisions (PubMed:12571286, PubMed:21816348) . Has guanine nucleotide dissociation inhibitor (GDI) activity towards G (i) alpha proteins, such as GNAI1 and GNAI3, and thereby regulates their activity (PubMed:22952234) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse G-protein signalling modulator 2 (AGS3-like, C. elegans) (Gpsm2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
6230410J09Rik; LGN; Pins
Gene ID
76123
UniProt
Q8VDU0, Q3UPG3
Accession Number mRNA
NM_029522
Chromosomal Location
3 F3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
74.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Gpsm2
Species
Mouse
Protein ID
NP_083798
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/76123
Uniprot URL
https://www.uniprot.org/uniprot/Q8VDU0
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_029522
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_083798
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