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Stim1 (NM_009287) Mouse Recombinant Protein

Selected Variant

PM45285M5

Size: 20 µg

Product Specifications

Background

Plays a role in mediating store-operated Ca (2+) entry (SOCE), a Ca (2+) influx following depletion of intracellular Ca (2+) stores. Acts as Ca (2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca (2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca (2+) release-activated Ca (2+) (CRAC) channel subunit ORAI1. Involved in enamel formation. Activated following interaction with STIMATE, leading to promote STIM1 conformational switch.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse stromal interaction molecule 1 (Stim1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

SIM

Gene ID

20866

UniProt

P70302

Accession Number mRNA

NM_009287

Chromosomal Location

7 54.71 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

77.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Stim1

Species

Mouse

Protein ID

NP_033313

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/20866

Uniprot URL

https://www.uniprot.org/uniprot/P70302

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_009287

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_033313

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