Stim1 (NM_009287) Mouse Recombinant Protein
Selected Variant
PM45285M5
Size: 20 µg
Product Specifications
Background
Plays a role in mediating store-operated Ca (2+) entry (SOCE), a Ca (2+) influx following depletion of intracellular Ca (2+) stores. Acts as Ca (2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca (2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca (2+) release-activated Ca (2+) (CRAC) channel subunit ORAI1. Involved in enamel formation. Activated following interaction with STIMATE, leading to promote STIM1 conformational switch.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse stromal interaction molecule 1 (Stim1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
SIM
Gene ID
20866
UniProt
P70302
Accession Number mRNA
NM_009287
Chromosomal Location
7 54.71 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
77.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Stim1
Species
Mouse
Protein ID
NP_033313
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/20866
Uniprot URL
https://www.uniprot.org/uniprot/P70302
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_009287
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_033313
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