Rfx2 (NM_009056) Mouse Recombinant Protein
Product Specifications
Background
Transcription factor that acts as a key regulator of spermatogenesis (PubMed:26248850, PubMed:26162102, PubMed:26853561) . Acts by regulating expression of genes required for the haploid phase during spermiogenesis, such as genes required for cilium assembly and function (PubMed:26162102, PubMed:26853561) . Recognizes and binds the X-box, a regulatory motif with DNA sequence 5'-GTNRCC (0-3N) RGYAAC-3' present on promoters (PubMed:15229132, PubMed:26162102) . Probably activates transcription of the testis-specific histone gene HIST1H1T (PubMed:15229132) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse regulatory factor X, 2 (influences HLA class II expression) (Rfx2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
5430432H19Rik
Gene ID
19725
UniProt
P48379
Accession Number mRNA
NM_009056
Chromosomal Location
17 29.5 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
77 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Rfx2
Species
Mouse
Protein ID
NP_033082
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/19725
Uniprot URL
https://www.uniprot.org/uniprot/P48379
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_009056
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_033082
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