Capn2 (NM_009794) Mouse Recombinant Protein
Product Specifications
Background
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (By similarity) . Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs (PubMed:22711986) .[UniProtKB/Swiss-Prot Function]
Synonyms
AI326419; Capa-2; Capa2; m-calpain; m-calpin
Gene ID
12334
UniProt
O08529
Accession Number mRNA
NM_009794
Chromosomal Location
1 H5
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
80.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Capn2
Species
Mouse
Protein ID
NP_033924
Overview
Purified recombinant protein of Mouse calpain 2 (Capn2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/12334
Uniprot URL
https://www.uniprot.org/uniprot/O08529
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_009794
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_033924
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