Kif3a (NM_008443) Mouse Recombinant Protein

Product Specifications

Background

Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro. Plays a role in primary cilia formation (PubMed:21670265) . Plays a role in centriole cohesion and subdistal appendage organization and function. Regulates the formation of the subdistal appendage via recruitement of DCTN1 to the centriole. Also required for ciliary basal feet formation and microtubule anchoring to mother centriole (PubMed:23386061) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse kinesin family member 3A (Kif3a), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

Kif3; Kifl; Kns3

Gene ID

16568

UniProt

P28741, Q3UF02

Accession Number mRNA

NM_008443

Chromosomal Location

11 31.97 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

80.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.