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L3mbtl2 (NM_145993) Mouse Recombinant Protein

Selected Variant

PM45240M5

Size: 20 µg

Product Specifications

Background

Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27' (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse L3MBTL2 polycomb repressive complex 1 subunit (L3mbtl2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

4732493N06Rik; M4mbt

Gene ID

214669

UniProt

P59178

Accession Number mRNA

NM_145993

Chromosomal Location

15 E1

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

79.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

L3mbtl2

Species

Mouse

Protein ID

NP_666105

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/214669

Uniprot URL

https://www.uniprot.org/uniprot/P59178

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_145993

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_666105

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