Shkbp1 (NM_138676) Mouse Recombinant Protein
Product Specifications
Background
Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation (PubMed:21830225) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse Sh3kbp1 binding protein 1 (Shkbp1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
B930062H15Rik; Sb1
Gene ID
192192
UniProt
Q6P7W2
Accession Number mRNA
NM_138676
Chromosomal Location
7 A3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
76.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Shkbp1
Species
Mouse
Protein ID
NP_619617
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/192192
Uniprot URL
https://www.uniprot.org/uniprot/Q6P7W2
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_138676
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_619617
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