Sec14l1 (NM_001166507) Mouse Recombinant Protein
Product Specifications
Background
May play a role in innate immunity by inhibiting the antiviral RIG-I signaling pathway. In this pathway, functions as a negative regulator of DDX58/RIG-I, the cytoplasmic sensor of viral nucleic acids. Prevents the interaction of DDX58 with MAVS/IPS1, an important step in signal propagation. May also regulate the SLC18A3 and SLC5A7 cholinergic transporters.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse SEC14-like lipid binding 1 (Sec14l1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
1200017E04Rik; 2810012L19Rik; Naa-35
Gene ID
74136
UniProt
A8Y5H7
Accession Number mRNA
NM_001166507
Chromosomal Location
11 E2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
81.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Sec14l1
Species
Mouse
Protein ID
NP_001159979
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/74136
Uniprot URL
https://www.uniprot.org/uniprot/A8Y5H7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001166507
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001159979
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