Mad1l1 (NM_010752) Mouse Recombinant Protein
Selected Variant
PM45198M5
Size: 20 µg
Product Specifications
Background
Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. May recruit MAD2L1 to unattached kinetochores. Has a role in the correct positioning of the septum. Required for anchoring MAD2L1 to the nuclear periphery. Binds to the TERT promoter and represses telomerase expression, possibly by interfering with MYC binding.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse MAD1 mitotic arrest deficient 1-like 1 (Mad1l1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
AI173502; AW550425; Mad1
Gene ID
17120
UniProt
Q9WTX8
Accession Number mRNA
NM_010752
Chromosomal Location
5 78.82 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
83.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Mad1l1
Species
Mouse
Protein ID
NP_034882
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/17120
Uniprot URL
https://www.uniprot.org/uniprot/Q9WTX8
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_010752
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_034882
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