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Lrsam1 (NM_199302) Mouse Recombinant Protein

Product Specifications

Background

E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivate the ability of TSG101 to sort endocytic (EGF receptors) and exocytic (viral proteins) cargos (By similarity) . Bacterial recognition protein that defends the cytoplasm from invasive pathogens (By similarity) . Localizes to several intracellular bacterial pathogens and generates the bacteria-associated ubiquitin signal leading to autophagy-mediated intracellular bacteria degradation (xenophagy) (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse leucine rich repeat and sterile alpha motif containing 1 (Lrsam1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

MGC56830

Gene ID

227738

UniProt

Q80ZI6

Accession Number mRNA

NM_199302

Chromosomal Location

2 B

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

84 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Lrsam1

Species

Mouse

Protein ID

NP_955006

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/227738

Uniprot URL

https://www.uniprot.org/uniprot/Q80ZI6

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_199302

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_955006

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