Elmo2 (NM_207706) Mouse Recombinant Protein
Product Specifications
Background
Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
1190002F24Rik; CED-12
Gene ID
140579
UniProt
Q8BHL5
Accession Number mRNA
NM_207706
Chromosomal Location
2 H3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
83.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Elmo2
Species
Mouse
Protein ID
NP_997589
Overview
Purified recombinant protein of Mouse engulfment and cell motility 2 (Elmo2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/140579
Uniprot URL
https://www.uniprot.org/uniprot/Q8BHL5
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_207706
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_997589
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