Med15 (NM_001040683) Mouse Recombinant Protein
Product Specifications
Background
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for cholesterol-dependent gene regulation. Positively regulates the Nodal signaling pathway (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
A230074L19Rik; AW536074; mPcqap; Pcqap
Gene ID
94112
UniProt
Q6KAM1, E9Q7C1
Accession Number mRNA
NM_001040683
Chromosomal Location
16 10.94 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
82.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Med15
Species
Mouse
Protein ID
NP_001035773
Overview
Purified recombinant protein of Mouse mediator complex subunit 15 (Med15), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/94112
Uniprot URL
https://www.uniprot.org/uniprot/Q6KAM1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001040683
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001035773
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