Git1 (NM_001004144) Mouse Recombinant Protein
Product Specifications
Background
GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine-phosphorylated paxillin in cytoplasmic complexes (By similarity) . Involved in the regulation of cytokinesis; the function may involve ENTR1 and PTPN13 (PubMed:23108400) .[UniProtKB/Swiss-Prot Function]
Synonyms
Cat-1; p95Cat
Gene ID
216963
UniProt
Q68FF6
Accession Number mRNA
NM_001004144
Chromosomal Location
11 B5
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
85.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Git1
Species
Mouse
Protein ID
NP_001004144
Overview
Purified recombinant protein of Mouse GIT ArfGAP 1 (Git1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/216963
Uniprot URL
https://www.uniprot.org/uniprot/Q68FF6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001004144
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001004144
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