Ptpn12 (NM_011203) Mouse Recombinant Protein
Selected Variant
PM45078M5
Size: 20 µg
Product Specifications
Background
Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades (PubMed:17070019) . Dephosphorylates cellular tyrosine kinases, such as ERBB2 and PTK2B/PYK2, and thereby regulates signaling via ERBB2 and PTK2B/PYK2. Selectively dephosphorylates ERBB2 phosphorylated at 'Tyr-1112', 'Tyr-1196', and/or 'Tyr-1248' (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse protein tyrosine phosphatase, non-receptor type 12 (Ptpn12), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
P19-PTP; PTP-P19; PTP-PEST; PTPG1
Gene ID
19248
UniProt
P35831
Accession Number mRNA
NM_011203
Chromosomal Location
5 A3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
87 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Ptpn12
Species
Mouse
Protein ID
NP_035333
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/19248
Uniprot URL
https://www.uniprot.org/uniprot/P35831
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_011203
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_035333
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