Kirrel3 (NM_001190912) Mouse Recombinant Protein

Synaptic adhesion molecule required for the formation of target-specific synapses (PubMed:23637329, PubMed:26575286) . Required for formation of target-specific synapses at hippocampal mossy fiber synapses. Required for formation of mossy fiber filopodia, the synaptic structures connecting dentate granule and GABA neurons. Probably acts as a homophilic adhesion molecule that promotes trans-cellular interactions and stabilize mossy fiber filipodia contact and subsequent synapse formation (PubMed:26575286) . Required for the coalescence of vomeronasal sensory neuron axons (PubMed:23637329) . May be involved in the hematopoietic supportive capacity of stroma cells; the secreted extracellular domain is directly responsible for supporting hematopoietic stem cells (PubMed:12665856) .[UniProtKB/Swiss-Prot Function]

Purified recombinant protein of Mouse kirre like nephrin family adhesion molecule 3 (Kirrel3), transcript variant C, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.