Supv3l1 (NM_181423) Mouse Recombinant Protein
Product Specifications
Background
Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA.[UniProtKB/Swiss-Prot Function]
Synonyms
6330443E10Rik
Gene ID
338359
UniProt
Q80YD1
Accession Number mRNA
NM_181423
Chromosomal Location
10 B4
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
87.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Supv3l1
Species
Mouse
Protein ID
NP_852088
Overview
Purified recombinant protein of Mouse suppressor of var1, 3-like 1 (S. cerevisiae) (Supv3l1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/338359
Uniprot URL
https://www.uniprot.org/uniprot/Q80YD1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_181423
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_852088
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