Itgb6 (NM_001159564) Mouse Recombinant Protein

Product Specifications

Background

Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin (By similarity) . It recognizes the sequence R-G-D in its ligands (PubMed:10025398) . ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (By similarity) . Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation (PubMed:10025398) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse integrin beta 6 (Itgb6), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

2210409C20Rik; 4831415H04Rik

Gene ID

16420

UniProt

Q9Z0T9

Accession Number mRNA

NM_001159564

Chromosomal Location

2 34.81 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

86.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.