Itgb6 (NM_001159564) Mouse Recombinant Protein
Product Specifications
Background
Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin (By similarity) . It recognizes the sequence R-G-D in its ligands (PubMed:10025398) . ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (By similarity) . Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation (PubMed:10025398) .[UniProtKB/Swiss-Prot Function]
Synonyms
2210409C20Rik; 4831415H04Rik
Gene ID
16420
UniProt
Q9Z0T9
Accession Number mRNA
NM_001159564
Chromosomal Location
2 34.81 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
86.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Itgb6
Species
Mouse
Protein ID
NP_001153036
Overview
Purified recombinant protein of Mouse integrin beta 6 (Itgb6), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/16420
Uniprot URL
https://www.uniprot.org/uniprot/Q9Z0T9
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001159564
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001153036
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