Map3k20 (NM_023057) Mouse Recombinant Protein

Stress-activated component of a protein kinase signal transduction cascade. Regulates the JNK and p38 pathways (PubMed:11042189) . Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14 (By similarity) . Pro-apoptotic. Role in regulation of S and G2 cell cycle checkpoint by direct phosphorylation of CHEK2 (By similarity) . Involved in limb development (PubMed:26755636) .[UniProtKB/Swiss-Prot Function]

Purified recombinant protein of Mouse mitogen-activated protein kinase kinase kinase 20 (Map3k20), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.