Mcm6 (NM_008567) Mouse Recombinant Protein
Product Specifications
Background
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.[UniProtKB/Swiss-Prot Function]
Synonyms
ASP-l1; D1Wsu22e; Mcmd6
Gene ID
17219
UniProt
P97311, Q542I2
Accession Number mRNA
NM_008567
Chromosomal Location
1 55.8 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
92.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Mcm6
Species
Mouse
Protein ID
NP_032593
Overview
Purified recombinant protein of Mouse minichromosome maintenance complex component 6 (Mcm6), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/17219
Uniprot URL
https://www.uniprot.org/uniprot/P97311
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_008567
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_032593
Curated Selection
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