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Nedd9 (NM_001111324) Mouse Recombinant Protein

Product Specifications

Background

Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May function in transmitting growth control signals between focal adhesions at the cell periphery and the mitotic spindle in response to adhesion or growth factor signals initiating cell proliferation. May play an important role in integrin beta-1 or B cell antigen receptor (BCR) mediated signaling in B- and T-cells. Integrin beta-1 stimulation leads to recruitment of various proteins including CRK, NCK and SHPTP2 to the tyrosine phosphorylated form (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse neural precursor cell expressed, developmentally down-regulated gene 9 (Nedd9), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

Cas-L; CasL; HEF1; MEF1; Nedd-9; p105

Gene ID

18003

UniProt

O35177

Accession Number mRNA

NM_001111324

Chromosomal Location

13 A3.3- A4

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

93.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Nedd9

Species

Mouse

Protein ID

NP_001104794

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/18003

Uniprot URL

https://www.uniprot.org/uniprot/O35177

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001111324

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001104794

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