Nedd9 (NM_001111324) Mouse Recombinant Protein
Product Specifications
Background
Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May function in transmitting growth control signals between focal adhesions at the cell periphery and the mitotic spindle in response to adhesion or growth factor signals initiating cell proliferation. May play an important role in integrin beta-1 or B cell antigen receptor (BCR) mediated signaling in B- and T-cells. Integrin beta-1 stimulation leads to recruitment of various proteins including CRK, NCK and SHPTP2 to the tyrosine phosphorylated form (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
Cas-L; CasL; HEF1; MEF1; Nedd-9; p105
Gene ID
18003
UniProt
O35177
Accession Number mRNA
NM_001111324
Chromosomal Location
13 A3.3- A4
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
93.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Nedd9
Species
Mouse
Protein ID
NP_001104794
Overview
Purified recombinant protein of Mouse neural precursor cell expressed, developmentally down-regulated gene 9 (Nedd9), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/18003
Uniprot URL
https://www.uniprot.org/uniprot/O35177
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001111324
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001104794
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