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Cmtr1 (NM_028791) Mouse Recombinant Protein

Selected Variant

PM44981M5

Size: 20 µg

Product Specifications

Background

S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m (7) GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m (7) GpppRm (cap1) . Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse cap methyltransferase 1 (Cmtr1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

1300018I05Rik; AI451264; Ftsjd2; MTr1

Gene ID

74157

UniProt

Q9DBC3

Accession Number mRNA

NM_028791

Chromosomal Location

17 A3.3

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

95.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Cmtr1

Species

Mouse

Protein ID

NP_083067

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/74157

Uniprot URL

https://www.uniprot.org/uniprot/Q9DBC3

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_028791

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_083067

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