Adamts4 (NM_172845) Mouse Recombinant Protein
Product Specifications
Background
This gene encodes a member of "a disintegrin and metalloproteinase with thrombospondin motifs" (ADAMTS) family of multi-domain matrix-associated metalloendopeptidases that have diverse roles in tissue morphogenesis and pathophysiological remodeling, in inflammation and in vascular biology. The encoded preproprotein undergoes proteolytic processing to generate an active zinc-dependent aggrecanase enzyme that degrades cartilage. [provided by RefSeq, Jul 2016]
Synonyms
ADAM-; ADAM-TS4; ADAMTS-2; ADMP-1
Gene ID
240913
UniProt
Q8BNJ2
Accession Number mRNA
NM_172845
Chromosomal Location
1 79.28 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
91.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Adamts4
Species
Mouse
Protein ID
NP_766433
Overview
Purified recombinant protein of Mouse a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 (Adamts4), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/240913
Uniprot URL
https://www.uniprot.org/uniprot/Q8BNJ2
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_172845
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_766433
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