Pik3c3 (BC024675) Mouse Recombinant Protein
Product Specifications
Background
Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for transport from early to late endosomes (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
5330434F23, Vps34
Gene ID
225326
UniProt
Q6PF93
Accession Number mRNA
BC024675
Chromosomal Location
18 B1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
96.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Pik3c3
Species
Mouse
Overview
Purified recombinant protein of Mouse phosphoinositide-3-kinase, class 3 (cDNA clone MGC:30377 IMAGE:3661094), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/225326
Uniprot URL
https://www.uniprot.org/uniprot/Q6PF93
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/BC024675
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