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Pik3c3 (BC024675) Mouse Recombinant Protein

Product Specifications

Background

Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for transport from early to late endosomes (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse phosphoinositide-3-kinase, class 3 (cDNA clone MGC:30377 IMAGE:3661094), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

5330434F23, Vps34

Gene ID

225326

UniProt

Q6PF93

Accession Number mRNA

BC024675

Chromosomal Location

18 B1

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

96.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Pik3c3

Species

Mouse

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/225326

Uniprot URL

https://www.uniprot.org/uniprot/Q6PF93

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/BC024675

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